Please use this identifier to cite or link to this item: http://cicy.repositorioinstitucional.mx/jspui/handle/1003/1498
Anti-inflammatory activity of critonia aromatisans and montanoa grandiflora leaves extracts, plants used in mayan traditional medicine to treat inflammation
Actividad antiinflamatoria de extractos de hojas de Critonia aromatisans y Montanoa grandiflora, plantas utilizadas en la Medicina Tradicional Maya para tratar la inflamación
Fabiola Elizabeth Villa de la Torre
ANA MARIA PUEBLA PEREZ
VICTOR ERMILO ARANA ARGAEZ
ROLFFY RUBEN ORTIZ ANDRADE
GREGORIO DE JESUS CARBALLO UICAB
MARTHA ELENA MENDEZ GONZALEZ
MIRBELLA DEL ROSARIO CACERES FARFAN
ROCIO DE LOURDES BORGES ARGAEZ
Acceso Abierto
Atribución-NoComercial-SinDerivadas
DOI: 10.18387/polibotanica.43.13
CRITONIA AROMATISANS
MONTANOA GRANDIFLORA
INFLAMMATION
CARRAGEENAN
NITRIC OXIDE
MACROPHAGES
The aim of the study is to investigate anti-inflammatory properties of polar and non-polar extracts prepared from Critonia aromatisans and Montanoa grandiflora, two common native species used in Mayan traditional ointments to treat inflammation, joint pain and rheumatism. The anti-inflammatory properties of methanol/acetonitrile and nhexane leaf extracts were tested in vivo and in vitro. The extracts of C. aromatisans and M. grandiflora decreased in a concentration-dependent manner lipopolysaccharide (LPS)-induced nitric oxide (NO) production without affecting the cell viability. the extracts of C. aromatisans at dose of 200 mg/kg exhibited substantial anti-inflammatory activity in the carrageenan-induced paw oedema test and 12-O-Tetradecanoylphorbol-13-acetate (TPA)-induced ear oedema inhibition assay with a reduction in inflammation of up to 90 and 80%, respectively. These results validate the traditional uses by Mayan communities that endorse the use of this species to treat inflammation.
2017
Artículo
Polibotánica, (43), 285-319, 2017
Inglés
Borges-Argáez, R. (2017). Anti-inflammatory activity of critonia aromatisans and montanoa grandiflora leaves extracts, plants used in mayan traditional medicine to treat inflammation. Polibotánica, (43), 285-319.
BIOLOGÍA Y QUÍMICA
Versión publicada
publishedVersion - Versión publicada
Appears in Collections:Artículos de Investigación Arbitrados

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