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Nanofibers of gelatin and polivinyl-alcohol-chitosan for wound dressing application: fabrication and characterization | |
PAOLA IVETH CAMPA SIQUEIROS Tomás J. Madera-Santana Jesús Fernando Ayala Zavala JAIME LOPEZ CERVANTES MARIA MONICA CASTILLO ORTEGA Pedro Jesús Herrera Franco | |
Acceso Abierto | |
Atribución-NoComercial-SinDerivadas | |
https://doi.org/10.1590/0104-1428.07919 | |
CHITOSAN ELECTROSPINNING GELATIN PVA WOUND DRESSING | |
Electrospun nanofibers from gelatin (G), chitosan (CS), and chitosan-polyvinyl alcohol (CS-PVA) were developed by electrospinning process. Mechanical properties were determined by the tensile test, the elastic modulus values of the nanofibers were G (15.418-34.34 MPa) and CS-PVA (17.44-126.427 MPa). The morphological characterization by SEM revealed that the systems with 15% G and 6% CS-PVA showed morphological homogeneity. Structural characterization by FTIR indicated an interaction among some functional groups of the component. Thermal analysis by DSC and TGA showed degradation temperatures for G (330 °C), CS (210 °C to 370 °C), and PVA (310 °C to 420 °C). The contact angles values denoted the hydrophilic nature of the material. Finally, the antimicrobial assay proved that both 15% G and 7% PVA on the CS-PVA system presented the best antimicrobial effect. The results indicate that the electrospun nanofibers fabricated with G or CS-PVA can be used as wound healing dressings. | |
2020 | |
Artículo | |
Polímeros, 30(1), 2020 | |
Inglés | |
Campa-Siqueiros, P., Madera-Santana, T. J., Ayala-Zavala, J. F., López-Cervantes, J., Castillo-Ortega, M. M., & Herrera-Franco, P. J. (2020). Nanofibers of gelatin and polivinyl-alcohol-chitosan for wound dressing application: fabrication and characterization. Polímeros, 30(1). | |
PROPIEDADES DE LOS MATERIALES | |
Versión publicada | |
publishedVersion - Versión publicada | |
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