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Antibacterial activity of a glass ionomer cement doped with copper nanoparticles
DAVID ALEJANDRO AGUILAR PEREZ
ROSSANA FARIDE VARGAS CORONADO
JOSE MANUEL CERVANTES UC
NAYELI RODRIGUEZ FUENTES
Conrado Aparicio
CRISTIAN COVARRUBIAS CERDA
MARCO ANTONIO ALVAREZ PEREZ
VICTOR IRAHUEN GARCIA PEREZ
MIRYAM MARTINEZ HERNANDEZ
JUAN VALERIO CAUICH RODRIGUEZ
Acceso Abierto
Atribución-NoComercial-SinDerivadas
doi:10.4012/dmj.2019-046
ANAEROBIA BACTERIA
BIOMATERIAL
DENTAL CEMENT
FIBROBLAST
METAL NANOPARTICLE
Copper nanoparticles (NCu) were synthetized and added to commercial glass ionomer cement, to evaluate in vitro its antibacterial activity against oral cavity strains. The NCu were synthesized by copper acetate reduction with L-ascorbic acid and characterized by FTIR, Raman, XPS, XRD and TEM. Then, commercial glass ionomer cement (GIC) was modified (MGIC) with various concentrations of NCu and physicochemically characterized. Cell viability was tested against human dental pulp fibroblasts (HDPFs) by Alamar-Blue assay and antibacterial test was performed against S. mutans and S. sanguinis by colony forming unit (CFU) growth method. Synthesized NCu rendered a mixture of both metallic copper and cuprous oxide (Cu2O). HDPF viability reduces with exposure time to the extracts (68-72% viability) and MGIC with 2-4 wt% NCu showed antimicrobial activity against the two tested strains.
2020
Artículo
Dent Mater J. 2020 Jun 5;39(3):389-396. doi: 10.4012/dmj.2019-046. Epub 2020 Mar 24. PMID: 32213765.
Inglés
Aguilar-Perez D, Vargas-Coronado R, Cervantes-Uc JM, Rodriguez-Fuentes N, Aparicio C, Covarrubias C, Alvarez-Perez M, Garcia-Perez V, Martinez-Hernandez M, Cauich-Rodriguez JV. Antibacterial activity of a glass ionomer cement doped with copper nanoparticles. Dent Mater J. 2020 Jun 5;39(3):389-396. doi: 10.4012/dmj.2019-046. Epub 2020 Mar 24. PMID: 32213765.
PROPIEDADES DE LOS MATERIALES
Versión publicada
publishedVersion - Versión publicada
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