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http://cicy.repositorioinstitucional.mx/jspui/handle/1003/1896| Modification of Ceiba pentandra cellulose for drug release applications | |
| SILVIA ARGELIA PERAZA KU JOSE MANUEL CERVANTES UC Beatriz Escobar Morales Jorge Alonso Uribe Calderón | |
| Acceso Abierto | |
| Atribución-NoComercial-SinDerivadas | |
| 10.1515/epoly-2020-0025 | |
| 10.1515/epoly-2020-0025 | |
| CEIBA PENTANDRA CHLORHEXIDINE DIACETATE CELLULOSE CROSS-LINKING DRUG RELEASE | |
| Tubular fibers (raw and wax-free) from Ceiba pentandra (CP) were cross-linked with butane-1,2,3,4-tetracarboxylic acid (BTCA) at different concentrations to obtain a porous biodegradable medium for drug release applications. Chlorhexidine diacetate (CHX) was added to the cross-linked fibers for drug release studies. The Fourier transform infrared spectroscopy, thermogravimetric analysis, and scanning electron microscopy results indicated that the cross-linked fibers with a 5:1 fiber:BTCA ratio presented the higher cross-linking density. CHX was added at different concentrations (8% and 16% wt/wt); the elemental analysis indicated that CHX was loaded up to 7.99 wt%. In vitro studies showed a burst release of CHX within the first 3 h. CHX release kinetics was described using several models, with the Korsmeyer–Peppas equation, which adjusted better to the experimental data. The results indicated that the CP fibers are a feasible material for drug release applications. | |
| 2020 | |
| Artículo | |
| e-Polymers, 20(1), 194-202, 2020 | |
| Inglés | |
| Peraza-Ku, S. A., Cervantes-Uc, J. M., Escobar-Morales, B., & Uribe-Calderon, J. A. (2020). Modification of Ceiba pentandra cellulose for drug release applications. e-Polymers, 20(1), 194-202. | |
| RESISTENCIA DE MATERIALES | |
| Versión publicada | |
| publishedVersion - Versión publicada | |
| Aparece en las colecciones: | Artículos de Investigación Arbitrados |
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