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Mulinane-and Azorellane-type diterpenoids: A systematic review of their biosynthesis, chemistry, and pharmacology
Angel de Jesús Dzul Beh
ANDRES HUMBERTO UC CACHON
Jorge Borquez
luis loyola
Luis Manuel Peña Rodríguez
GLORIA MARIA MOLINA SALINAS
Acceso Abierto
Atribución-NoComercial-SinDerivadas
10.3390/biom10091333
MULINANE
AZORELLANE
DITERPENOIDS
ANTIMYCOBACTERIAL
ANTIULCER
Mulinane- and azorellane-type diterpenoids have unique tricyclic fused five-, six-, and seven-membered systems and a wide range of biological properties, including antimicrobial, antiprotozoal, spermicidal, gastroprotective, and anti-inflammatory, among others. These secondary metabolites are exclusive constituents of medicinal plants belonging to the Azorella, Laretia, and Mulinum genera. In the last 30 years, more than 95 mulinanes and azorellanes have been reported, 49 of them being natural products, 4 synthetics, and the rest semisynthetic and biotransformed derivatives. This systematic review highlights the biosynthetic origin, the chemistry, and the pharmacological activities of this remarkably interesting group of diterpenoids. 
2020
Artículo
Biomolecules, 10(9), 1333, 2020.
Inglés
Dzul-Beh, A. D. J., Uc-Cachón, A. H., Bórquez, J., Loyola, L. A., Peña-Rodríguez, L. M., & Molina-Salinas, G. M. (2020). Mulinane-and Azorellane-type diterpenoids: A systematic review of their biosynthesis, chemistry, and pharmacology. Biomolecules, 10(9), 1333.
BIOLOGÍA MOLECULAR DE PLANTAS
Versión publicada
publishedVersion - Versión publicada
Aparece en las colecciones: Artículos de Investigación Arbitrados

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