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Phage therapy for crops: concepts, experimental and bioinformatics approaches to direct Its application
José Luis Villalpando Aguilar
GILBERTO MATOS PECH
Itzel López-Rosas
HUGO CASTELÁN SÁNCHEZ
FULGENCIO ALATORRE COBOS
Acceso Abierto
Atribución-NoComercial-SinDerivadas
https://doi.org/10.3390/ijms24010325
BACTERIOPHAGES
GENOMICS
PHAGE THERAPY
CROP
BIOINFORMATICS
PHAGE GENOME
BIOCONTROL
Phage therapy consists of applying bacteriophages, whose natural function is to kill specific bacteria. Bacteriophages are safe, evolve together with their host, and are environmentally friendly. At present, the indiscriminate use of antibiotics and salt minerals (Zn2+ or Cu2+) has caused the emergence of resistant strains that infect crops, causing difficulties and loss of food production. Phage therapy is an alternative that has shown positive results and can improve the treatments available for agriculture. However, the success of phage therapy depends on finding effective bacteriophages. This review focused on describing the potential, up to now, of applying phage therapy as an alternative treatment against bacterial diseases, with sustainable improvement in food production. We described the current isolation techniques, characterization, detection, and selection of lytic phages, highlighting the importance of complementary studies using genome analysis of the phage and its host. Finally, among these studies, we concentrated on the most relevant bacteriophages used for biocontrol of Pseudomonas spp., Xanthomonas spp., Pectobacterium spp., Ralstonia spp., Burkholderia spp., Dickeya spp., Clavibacter michiganensis, and Agrobacterium tumefaciens as agents that cause damage to crops, and affect food production around the world.
2023
Artículo
Int. J. Mol. Sci. 24, 325, 2023.
Inglés
Villalpando-Aguilar, J.L.; Matos-Pech, G.; López-Rosas, I.; Castelán-Sánchez, H.G.; Alatorre-Cobos, F. Phage therapy for crops: concepts, experimental and bioinformatics approaches to direct its application. Int. J. Mol. Sci. 2023,24, 325. https://doi.org/10.3390/ijms24010325
BIOLOGÍA MOLECULAR DE PLANTAS
Versión publicada
publishedVersion - Versión publicada
Aparece en las colecciones: Artículos de Investigación Arbitrados

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